Chemo‐ and Enantioselective Photoenzymatic Ketone Reductions Using a Promiscuous Flavin‐dependent Nitroreductase
نویسندگان
چکیده
The enantioselective photoenzymatic reduction of a wide variety ketones to the corresponding alcohols using promiscuous nitroreductase BaNTR1 is reported. This flavoenzyme not only shows outstanding enantioselectivity but also remarkably high chemoselectivity, promoting various α,ß-unsaturated give desired enantioenriched without reducing C=C or C≡C bond.
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ژورنال
عنوان ژورنال: Chemcatchem
سال: 2022
ISSN: ['1867-3899', '1867-3880']
DOI: https://doi.org/10.1002/cctc.202200043